Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001081550.2

p.I1213L

c.3637A>C

Surrounding Variants

1 paper

NM_001081550.2

p.I1213L

c.3637A>T

3 papers

NM_001081550.2

p.H1187Y

c.3559C>T

1 paper

NM_001081550.2

p.M1180I

c.3540G>T

1 paper

NM_001081550.2

p.M1180I

c.3540G>C

1 paper

NM_001081550.2

p.M1180I

c.3540G>A

1 paper

NM_001081550.2

p.D1228Splc

c.3683-16C>T

3 papers

NM_001081550.2

p.N1261H

c.3781A>C

3 papers

NM_001081550.2

p.G1168Splc

c.3503+4A>C

3 papers

NM_001081550.2

p.R1121G

c.3361A>G

3 papers

NM_001081550.2

p.S1108L

c.3323C>T

1 paper

NM_001081550.2

p.Y1102C

c.3305A>G

2 papers

NM_001081550.2

p.W1100C

c.3300G>T