Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001081550.2

p.Y881C

c.2642A>G

Surrounding Variants

1 paper

NM_001081550.2

p.E927fs

c.2779_2780fs

1 paper

NM_001081550.2

p.V952I

c.2854G>A

1 paper

NM_001081550.2

p.E959G

c.2876A>G

2 papers

NM_001081550.2

p.C981Y

c.2942G>A

4 papers

NM_001081550.2

p.S1012P

c.3034T>C

1 paper

NM_001081550.2

p.K1062N

c.3186G>T

1 paper

NM_001081550.2

p.K1062N

c.3186G>C

2 papers

NM_001081550.2

p.R1075W

c.3223C>T

2 papers

NM_001081550.2

p.W1100C

c.3300G>T

2 papers

NM_001081550.2

p.W1100C

c.3300G>C

1 paper

NM_001081550.2

p.Y1102C

c.3305A>G

3 papers

NM_001081550.2

p.S1108L

c.3323C>T