Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001081550.2

p.I800T

c.2399T>C

Surrounding Variants

1 paper

NM_001081550.2

p.S827L

c.2480C>T

1 paper

NM_001081550.2

p.G767R

c.2299G>C

1 paper

NM_001081550.2

p.G767R

c.2299G>A

1 paper

NM_001081550.2

p.A747S

c.2239G>T

1 paper

NM_001081550.2

p.L729fs

c.2185_2186fs

2 papers

NM_001081550.2

p.K724E

c.2170A>G

1 paper

NM_001081550.2

p.K723E

c.2167A>G

1 paper

NM_001081550.2

p.G713fs

c.2137_2138fs

3 papers

NM_001081550.2

p.G713D

c.2138G>A

2 papers

NM_001081550.2

p.T696I

c.2087C>T

1 paper

NM_001081550.2

p.Q684insFs

c.2051_2052insA

1 paper

NM_001081550.2

p.M686fs

c.2056_2057fs