Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001081550.2

p.Q567P

c.1700A>C

Surrounding Variants

1 paper

NM_001081550.2

p.R555C

c.1663C>T

1 paper

NM_001081550.2

p.R555S

c.1663C>A

1 paper

NM_001081550.2

p.K554delFs

c.1662delC

1 paper

NM_001081550.2

p.Q588Q

c.1764G>A

1 paper

NM_001081550.2

p.Y590S

c.1769A>C

1 paper

NM_001081550.2

p.L601L

c.1801T>C

1 paper

NM_001081550.2

p.D610N

c.1828G>A

1 paper

NM_001081550.2

p.E624A

c.1871A>C

1 paper

NM_001081550.2

p.K540N

c.1620A>T

1 paper

NM_001081550.2

p.K540N

c.1620A>C

1 paper

NM_001081550.2

p.H535R

c.1604A>G

7 papers

NM_001081550.2

p.Y517C

c.1550A>G