Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001081550.2

p.E462K

c.1384G>A

Surrounding Variants

5 papers

NM_001081550.2

p.L438P

c.1313T>C

3 papers

NM_001081550.2

p.A421T

c.1261G>A

1 paper

NM_001081550.2

p.P418T

c.1252C>A

1 paper

NM_001081550.2

p.L394F

c.1180C>T

1 paper

NM_001081550.2

p.A382T

c.1144G>A

1 paper

NM_001081550.2

p.A373V

c.1118C>T

1 paper

NM_001081550.2

p.P370L

c.1109C>T

1 paper

NM_001081550.2

p.L353L

c.1059A>G

1 paper

NM_001081550.2

p.R326Q

c.977G>A

1 paper

NM_001081550.2

p.L318*

c.953T>A

4 papers

NM_001081550.2

p.L313F

c.937C>T

1 paper

NM_001081550.2

p.C294F

c.881G>T