Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001081550.2

p.I214V

c.640A>G

Surrounding Variants

1 paper

NM_001081550.2

p.E219Q

c.655G>C

1 paper

NM_001081550.2

p.N208S

c.623A>G

1 paper

NM_001081550.2

p.P241L

c.722C>T

1 paper

NM_001081550.2

p.D190N

c.568G>A

1 paper

NM_001081550.2

p.T188A

c.562A>G

1 paper

NM_001081550.2

p.K174R

c.521A>G