Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001081550.2

p.D44Splc

c.131-2A>G

Surrounding Variants

1 paper

NM_001081550.2

p.F45I

c.133T>A

1 paper

NM_001081550.2

p.Q46K

c.136C>A

2 papers

NM_001081550.2

p.Y50S

c.149A>C

1 paper

NM_001081550.2

p.E64_Q65insT

c.190_194ins3

1 paper

NM_001081550.2

p.Q65Q

c.195G>A

1 paper

NM_001081550.2

p.V69A

c.206T>C

1 paper

NM_001081550.2

p.D72_I73del2

c.214_218del6

5 papers

NM_001081550.2

p.R77C

c.229C>T

1 paper

NM_001081550.2

p.H26Y

c.76C>T

1 paper

NM_001081550.2

p.F24_L25delFs

c.72_73delAA

1 paper

NM_001081550.2

p.D92Splc

c.275-7A>G

1 paper

NM_001081550.2

p.I93T

c.278T>C