Varaico: Literature-Extracted Genetic Variants

THOC6

59 papers

RefSeq Summary

This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/exp...

Pfam Domains

WD40aa 66–100UCSCWD domain, G-beta repeat

Beta-prop_NOL10_Naa 118–329UCSCNucleolar protein 10-like, N-terminal domain

Gene Aliases

HGNC Name

THO complex subunit 6

HGNC Previous Symbol

WDR58

Papers

RefSeq ID

Protein change

DNA change

1–12 of 69 variants

11 papers

NM_024339.5

p.W100R

c.298T>A

11 papers

NM_024339.5

p.G275D

c.824G>A

9 papers

NM_024339.5

p.W100R

c.298T>C

9 papers

NM_024339.5

p.V234L

c.700G>C

6 papers

NM_024339.5

p.G190E

c.569G>A

4 papers

NM_024339.5

p.G46R

c.136G>A

4 papers

NM_024339.5

p.G46R

c.136G>C

4 papers

NM_024339.5

p.R87*

c.259C>T

4 papers

NM_024339.5

p.W100*

c.299G>A

4 papers

NM_024339.5

p.Q204P

c.611A>C

3 papers

NM_024339.5

p.W100*

c.300G>A

2 papers

NM_024339.5

p.P6fs

c.16_17fs