Varaico: Literature-Extracted Genetic Variants

THOC6

59 papers

RefSeq Summary

This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/exp...

Pfam Domains

WD40aa 66–100UCSCWD domain, G-beta repeat

Beta-prop_NOL10_Naa 118–329UCSCNucleolar protein 10-like, N-terminal domain

Gene Aliases

HGNC Name

THO complex subunit 6

HGNC Previous Symbol

WDR58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_024339.5

p.W100*

c.300G>A

Surrounding Variants

4 papers

NM_024339.5

p.W100*

c.299G>A

11 papers

NM_024339.5

p.W100R

c.298T>A

9 papers

NM_024339.5

p.W100R

c.298T>C

4 papers

NM_024339.5

p.R87*

c.259C>T

1 paper

NM_024339.5

p.R115H

c.344G>A

1 paper

NM_024339.5

p.A74Splc

c.220+10C>G

2 papers

NM_024339.5

p.P68L

c.203C>T

1 paper

NM_024339.5

p.P127P

c.381T>G

2 papers

NM_024339.5

p.S52Splc

c.155+1G>T

1 paper

NM_024339.5

p.I50M

c.150C>G

1 paper

NM_024339.5

p.Q47H

c.141G>C

1 paper

NM_024339.5

p.Q47H

c.141G>T