Varaico: Literature-Extracted Genetic Variants

THOC6

59 papers

RefSeq Summary

This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/exp...

Pfam Domains

WD40aa 66–100UCSCWD domain, G-beta repeat

Beta-prop_NOL10_Naa 118–329UCSCNucleolar protein 10-like, N-terminal domain

Gene Aliases

HGNC Name

THO complex subunit 6

HGNC Previous Symbol

WDR58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_024339.5

p.G190E

c.569G>A

Surrounding Variants

2 papers

NM_024339.5

p.E188K

c.562G>A

1 paper

NM_024339.5

p.R193*

c.577C>T

1 paper

NM_024339.5

p.L184M

c.550C>A

1 paper

NM_024339.5

p.V163A

c.488T>C

1 paper

NM_024339.5

p.D196Splc

c.587-2A>G

4 papers

NM_024339.5

p.Q204P

c.611A>C

1 paper

NM_024339.5

p.E212_E213Splc

c.636+1G>A

1 paper

NM_024339.5

p.Q149*

c.445C>T

1 paper

NM_024339.5

p.D147H

c.439G>C

2 papers

NM_024339.5

p.W222R

c.664T>A

2 papers

NM_024339.5

p.W222R

c.664T>C

1 paper

NM_024339.5

p.P127P

c.381T>G