Varaico: Literature-Extracted Genetic Variants

THOC6

59 papers

RefSeq Summary

This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/exp...

Pfam Domains

WD40aa 66–100UCSCWD domain, G-beta repeat

Beta-prop_NOL10_Naa 118–329UCSCNucleolar protein 10-like, N-terminal domain

Gene Aliases

HGNC Name

THO complex subunit 6

HGNC Previous Symbol

WDR58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024339.5

p.W222R

c.664T>A

Surrounding Variants

2 papers

NM_024339.5

p.W222R

c.664T>C

1 paper

NM_024339.5

p.E212_E213Splc

c.636+1G>A

9 papers

NM_024339.5

p.V234L

c.700G>C

1 paper

NM_024339.5

p.V234F

c.700G>T

1 paper

NM_024339.5

p.G237delFs

c.709delG

1 paper

NM_024339.5

p.G237fs

c.709_710fs

1 paper

NM_024339.5

p.G238D

c.713G>A

4 papers

NM_024339.5

p.Q204P

c.611A>C

1 paper

NM_024339.5

p.L241insFs

c.721dupC

1 paper

NM_024339.5

p.L241fs

c.721_722fs

1 paper

NM_024339.5

p.R247*

c.739C>T

2 papers

NM_024339.5

p.R247Q

c.740G>A