Varaico: Literature-Extracted Genetic Variants

THOC6

59 papers

RefSeq Summary

This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/exp...

Pfam Domains

WD40aa 66–100UCSCWD domain, G-beta repeat

Beta-prop_NOL10_Naa 118–329UCSCNucleolar protein 10-like, N-terminal domain

Gene Aliases

HGNC Name

THO complex subunit 6

HGNC Previous Symbol

WDR58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_024339.5

p.G275D

c.824G>A

Surrounding Variants

1 paper

NM_024339.5

p.G275A

c.824G>C

2 papers

NM_024339.5

p.R278C

c.832C>T

1 paper

NM_024339.5

p.S297delFs

c.890delC

1 paper

NM_024339.5

p.L270_I271Splc

c.810+1G>A

1 paper

NM_024339.5

p.F266L

c.798C>A

1 paper

NM_024339.5

p.F266L

c.798C>G

1 paper

NM_024339.5

p.F266L

c.796T>C

1 paper

NM_024339.5

p.V264_T265delFs

c.792_793delCA

1 paper

NM_024339.5

p.V264I

c.790G>A

1 paper

NM_024339.5

p.K315_V316Splc

c.945+1G>A

1 paper

NM_024339.5

p.A259A

c.777G>C

1 paper

NM_024339.5

p.A259V

c.776C>T