Varaico: Literature-Extracted Genetic Variants

THRA

276 papers

RefSeq Summary

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of ...

Pfam Domains

zf-C4aa 51–122UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 204–379UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

thyroid hormone receptor alpha

HGNC Previous Symbols

THRA1; THRA2; ERBA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_199334.5

p.G207E

c.620G>A

Surrounding Variants

21 papers

NM_199334.5

p.D211G

c.632A>G

1 paper

NM_199334.5

p.E213D

c.639A>C

1 paper

NM_199334.5

p.E213D

c.639A>T

1 paper

NM_199334.5

p.A214G

c.641C>G

1 paper

NM_199334.5

p.I222V

c.664A>G

1 paper

NM_199334.5

p.T223A

c.667A>G

1 paper

NM_199334.5

p.L192_P193Splc

c.577-4C>T

2 papers

NM_199334.5

p.P224L

c.671C>T

3 papers

NM_199334.5

p.A225T

c.673G>A

1 paper

NM_199334.5

p.A225G

c.674C>G

1 paper

NM_199334.5

p.T227N

c.680C>A

2 papers

NM_199334.5

p.R228H

c.683G>A