Varaico: Literature-Extracted Genetic Variants

THRA

276 papers

RefSeq Summary

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of ...

Pfam Domains

zf-C4aa 51–122UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 204–379UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

thyroid hormone receptor alpha

HGNC Previous Symbols

THRA1; THRA2; ERBA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_199334.5

p.L274R

c.821T>G

Surrounding Variants

17 papers

NM_199334.5

p.L274P

c.821T>C

1 paper

NM_199334.5

p.T275M

c.824C>T

1 paper

NM_199334.5

p.L276_M280del5

c.826_839del15

7 papers

NM_199334.5

p.T273A

c.817A>G

1 paper

NM_199334.5

p.S271N

c.812G>A

1 paper

NM_199334.5

p.S271I

c.812G>T

1 paper

NM_199334.5

p.G278V

c.833G>T

1 paper

NM_199334.5

p.P269L

c.806C>T

1 paper

NM_199334.5

p.D268N

c.802G>A

1 paper

NM_199334.5

p.R266H

c.797G>A

1 paper

NM_199334.5

p.R266L

c.797G>T

1 paper

NM_199334.5

p.K283Q

c.847A>C