Varaico: Literature-Extracted Genetic Variants

THRA

276 papers

RefSeq Summary

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of ...

Pfam Domains

zf-C4aa 51–122UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 204–379UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

thyroid hormone receptor alpha

HGNC Previous Symbols

THRA1; THRA2; ERBA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_199334.5

p.I299V

c.895A>G

Surrounding Variants

1 paper

NM_199334.5

p.S296F

c.887C>T

1 paper

NM_199334.5

p.G303A

c.908G>C

1 paper

NM_199334.5

p.S305P

c.913T>C

9 papers

NM_199334.5

p.G291S

c.871G>A

1 paper

NM_199334.5

p.K288R

c.863A>G

1 paper

NM_199334.5

p.K288Q

c.862A>C

1 paper

NM_199334.5

p.K288E

c.862A>G

1 paper

NM_199334.5

p.L287V

c.859C>G

2 papers

NM_199334.5

p.Q286H

c.858G>C

2 papers

NM_199334.5

p.Q286H

c.858G>T

1 paper

NM_199334.5

p.T314M

c.941C>T

1 paper

NM_199334.5

p.K283R

c.848A>G