Varaico: Literature-Extracted Genetic Variants

THRA

276 papers

RefSeq Summary

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of ...

Pfam Domains

zf-C4aa 51–122UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 204–379UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

thyroid hormone receptor alpha

HGNC Previous Symbols

THRA1; THRA2; ERBA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_199334.5

p.E350K

c.1048G>A

Surrounding Variants

1 paper

NM_199334.5

p.F349L

c.1047C>A

1 paper

NM_199334.5

p.F349L

c.1047C>G

1 paper

NM_199334.5

p.F349L

c.1045T>C

3 papers

NM_199334.5

p.A348A

c.1044G>T

6 papers

NM_199334.5

p.H351Q

c.1053C>A

6 papers

NM_199334.5

p.H351Q

c.1053C>G

1 paper

NM_199334.5

p.A348S

c.1042G>T

1 paper

NM_199334.5

p.Y352C

c.1055A>G

2 papers

NM_199334.5

p.V353I

c.1057G>A

1 paper

NM_199334.5

p.L346V

c.1036C>G

1 paper

NM_199334.5

p.L346L

c.1036C>T

1 paper

NM_199334.5

p.E343A

c.1028A>C