Varaico: Literature-Extracted Genetic Variants

THRB

550 papers

RefSeq Summary

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of ...

Pfam Domains

zf-C4aa 105–176UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 263–445UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

thyroid hormone receptor beta

HGNC Previous Symbols

ERBA2; PRTH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001354712.2

p.E445*

c.1333G>T

Surrounding Variants

1 paper

NM_001354712.2

p.V444A

c.1331T>C

8 papers

NM_001354712.2

p.C446R

c.1336T>C

3 papers

NM_001354712.2

p.C446S

c.1336T>A

3 papers

NM_001354712.2

p.C446S

c.1337G>C

6 papers

NM_001354712.2

p.C446*

c.1338C>A

1 paper

NM_001354712.2

p.M442_K443delFs

c.1326_1327delTC

2 papers

NM_001354712.2

p.P447T

c.1339C>A

1 paper

NM_001354712.2

p.K443*

c.1327A>T

13 papers

NM_001354712.2

p.K443E

c.1327A>G

2 papers

NM_001354712.2

p.M442_K443delins

c.1326_1327delinsAT

2 papers

NM_001354712.2

p.P447L

c.1340C>T

9 papers

NM_001354712.2

p.M442T

c.1325T>C