Varaico: Literature-Extracted Genetic Variants

TIAM2

108 papers

RefSeq Summary

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (G...

Pfam Domains

PHaa 507–620UCSCPH domain

Tiam_CC_Exaa 645–742UCSCT-lymphoma invasion and metastasis CC-Ex domain

PDZaa 890–972UCSCPDZ domain

RhoGEFaa 1103–1291UCSCRhoGEF domain

PH_Tiam1aa 1300–1470UCSCTiam1 second PH domain-like

Gene Aliases

HGNC Name

TIAM Rac1 associated GEF 2

HGNC Alias Symbol

STEF

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_012454.4

p.G1699R

c.5095G>C

Surrounding Variants

2 papers

NM_012454.4

p.G1699R

c.5095G>A

1 paper

NM_012454.4

p.G1647E

c.4940G>A

1 paper

NM_012454.4

p.S1641R

c.4923C>A

1 paper

NM_012454.4

p.S1641R

c.4923C>G

1 paper

NM_012454.4

p.S1641R

c.4921A>C

1 paper

NM_012454.4

p.F1632L

c.4896C>A

1 paper

NM_012454.4

p.F1632L

c.4896C>G

1 paper

NM_012454.4

p.F1632L

c.4894T>C

1 paper

NM_012454.4

p.E1623Q

c.4867G>C

1 paper

NM_012454.4

p.G1618C

c.4852G>T

1 paper

NM_012454.4

p.I1590N

c.4769T>A

1 paper

NM_012454.4

p.H1575Y

c.4723C>T