Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

1–12 of 170 variants

8 papers

NM_182919.4

p.S160F

c.479C>T

8 papers

NM_182919.4

p.S186L

c.557C>T

7 papers

NM_182919.4

p.A568T

c.1702G>A

6 papers

NM_182919.4

p.R141*

c.421C>T

5 papers

NM_182919.4

p.S60C

c.179C>G

4 papers

NM_182919.4

p.M1V

c.1A>G

4 papers

NM_182919.4

p.V80M

c.238G>A

4 papers

NM_182919.4

p.P625L

c.1874C>T

3 papers

NM_182919.4

p.R180C

c.538C>T

3 papers

NM_182919.4

p.P234S

c.700C>T

3 papers

NM_182919.4

p.Q248R

c.743A>G

3 papers

NM_182919.4

p.P367del1

c.1099_1101delAGG