Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.T640S

c.1919C>G

Surrounding Variants

1 paper

NM_182919.4

p.T640S

c.1918A>T

1 paper

NM_182919.4

p.A638V

c.1913C>T

1 paper

NM_182919.4

p.P642fs

c.1924_1925fs

1 paper

NM_182919.4

p.P643P

c.1929G>A

1 paper

NM_182919.4

p.L633Q

c.1898T>A

4 papers

NM_182919.4

p.P625L

c.1874C>T

1 paper

NM_182919.4

p.P620_F621del2

c.1858_1862del6

1 paper

NM_182919.4

p.P619Q

c.1856C>A

1 paper

NM_182919.4

p.P614S

c.1840C>T

1 paper

NM_182919.4

p.Q612fs

c.1834_1835fs

1 paper

NM_182919.4

p.G611insFs

c.1832dupG

1 paper

NM_182919.4

p.G611C

c.1831G>T