Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182919.4

p.G592R

c.1774G>C

Surrounding Variants

2 papers

NM_182919.4

p.G592R

c.1774G>A

2 papers

NM_182919.4

p.Q588P

c.1763A>C

3 papers

NM_182919.4

p.G598W

c.1792G>T

1 paper

NM_182919.4

p.L574V

c.1720C>G

1 paper

NM_182919.4

p.G611C

c.1831G>T

1 paper

NM_182919.4

p.G611insFs

c.1832dupG

1 paper

NM_182919.4

p.Q612fs

c.1834_1835fs

1 paper

NM_182919.4

p.P614S

c.1840C>T

7 papers

NM_182919.4

p.A568T

c.1702G>A

1 paper

NM_182919.4

p.P619Q

c.1856C>A

1 paper

NM_182919.4

p.P620_F621del2

c.1858_1862del6

1 paper

NM_182919.4

p.R560Q

c.1679G>A