Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.E559A

c.1676A>C

Surrounding Variants

2 papers

NM_182919.4

p.R560W

c.1678C>T

1 paper

NM_182919.4

p.R560Q

c.1679G>A

2 papers

NM_182919.4

p.D557D

c.1671C>T

1 paper

NM_182919.4

p.D557N

c.1669G>A

1 paper

NM_182919.4

p.Q554R

c.1661A>G

2 papers

NM_182919.4

p.Q554*

c.1660C>T

1 paper

NM_182919.4

p.E551K

c.1651G>A

7 papers

NM_182919.4

p.A568T

c.1702G>A

1 paper

NM_182919.4

p.L574V

c.1720C>G

1 paper

NM_182919.4

p.E543A

c.1628A>C

1 paper

NM_182919.4

p.Q534K

c.1600C>A

2 papers

NM_182919.4

p.Q588P

c.1763A>C