Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.L513M

c.1537C>A

Surrounding Variants

2 papers

NM_182919.4

p.A521T

c.1561G>A

1 paper

NM_182919.4

p.K523R

c.1568A>G

1 paper

NM_182919.4

p.A525T

c.1573G>A

1 paper

NM_182919.4

p.Q498R

c.1493A>G

1 paper

NM_182919.4

p.P496P

c.1488G>A

1 paper

NM_182919.4

p.K529R

c.1586A>G

1 paper

NM_182919.4

p.Q534K

c.1600C>A

1 paper

NM_182919.4

p.C485Y

c.1454G>A

1 paper

NM_182919.4

p.E543A

c.1628A>C

1 paper

NM_182919.4

p.Q480_G481delFs

c.1438_1442del5

2 papers

NM_182919.4

p.R479Q

c.1436G>A

1 paper

NM_182919.4

p.T478K

c.1433C>A