Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.K415R

c.1244A>G

Surrounding Variants

1 paper

NM_182919.4

p.R411L

c.1232G>T

1 paper

NM_182919.4

p.V421M

c.1261G>A

1 paper

NM_182919.4

p.D423N

c.1267G>A

1 paper

NM_182919.4

p.D405E

c.1215C>G

1 paper

NM_182919.4

p.D405E

c.1215C>A

1 paper

NM_182919.4

p.P434L

c.1301C>T

2 papers

NM_182919.4

p.F394L

c.1182C>G

2 papers

NM_182919.4

p.F394L

c.1182C>A

2 papers

NM_182919.4

p.F394L

c.1180T>C

2 papers

NM_182919.4

p.Q392K

c.1174C>A

1 paper

NM_182919.4

p.E391D

c.1173A>T

1 paper

NM_182919.4

p.E391D

c.1173A>C