Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.S373P

c.1117T>C

Surrounding Variants

2 papers

NM_182919.4

p.S368ins1

c.1102_1103insCCT

1 paper

NM_182919.4

p.P365_P366ins0

c.1093_1098dup6

3 papers

NM_182919.4

p.P367del1

c.1099_1101delAGG

2 papers

NM_182919.4

p.P367_S368ins1

c.1101_1102insCCT

1 paper

NM_182919.4

p.P367_S368ins2

c.1101_1102ins6

1 paper

NM_182919.4

p.P365ins1

c.1094_1095insCCC

1 paper

NM_182919.4

p.P365R

c.1094C>G

1 paper

NM_182919.4

p.P362ins1

c.1085_1086insCCC

1 paper

NM_182919.4

p.S389_S390insFs

c.1167_1168insC

1 paper

NM_182919.4

p.T354I

c.1061C>T

1 paper

NM_182919.4

p.E391D

c.1173A>T

1 paper

NM_182919.4

p.E391D

c.1173A>C