Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182919.4

p.D289E

c.867T>G

Surrounding Variants

2 papers

NM_182919.4

p.D289E

c.867T>A

2 papers

NM_182919.4

p.P288L

c.863C>T

1 paper

NM_182919.4

p.G286A

c.857G>C

1 paper

NM_182919.4

p.E295K

c.883G>A

2 papers

NM_182919.4

p.D281E

c.843T>G

2 papers

NM_182919.4

p.D281E

c.843T>A

1 paper

NM_182919.4

p.N299S

c.896A>G

1 paper

NM_182919.4

p.Y300*

c.900C>G

1 paper

NM_182919.4

p.Y300*

c.900C>A

2 papers

NM_182919.4

p.P301S

c.901C>T

1 paper

NM_182919.4

p.P271_P276del0

c.811_828del18

1 paper

NM_182919.4

p.E306K

c.916G>A