Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182919.4

p.E252A

c.755A>C

Surrounding Variants

1 paper

NM_182919.4

p.E249K

c.745G>A

3 papers

NM_182919.4

p.Q248R

c.743A>G

1 paper

NM_182919.4

p.S258P

c.772T>C

1 paper

NM_182919.4

p.G245S

c.733G>A

1 paper

NM_182919.4

p.A262T

c.784G>A

1 paper

NM_182919.4

p.P242H

c.725C>A

2 papers

NM_182919.4

p.P240S

c.718C>T

1 paper

NM_182919.4

p.P268S

c.802C>T

3 papers

NM_182919.4

p.P234S

c.700C>T

1 paper

NM_182919.4

p.P271S

c.811C>T

1 paper

NM_182919.4

p.S228R

c.684C>G

1 paper

NM_182919.4

p.S228R

c.684C>A