Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182919.4

p.S228R

c.682A>C

Surrounding Variants

1 paper

NM_182919.4

p.S228R

c.684C>G

1 paper

NM_182919.4

p.S228R

c.684C>A

1 paper

NM_182919.4

p.R222H

c.665G>A

3 papers

NM_182919.4

p.P234S

c.700C>T

1 paper

NM_182919.4

p.S219C

c.655A>T

2 papers

NM_182919.4

p.P240S

c.718C>T

1 paper

NM_182919.4

p.T214A

c.640A>G

1 paper

NM_182919.4

p.P242H

c.725C>A

1 paper

NM_182919.4

p.S212A

c.634T>G

1 paper

NM_182919.4

p.G245S

c.733G>A

1 paper

NM_182919.4

p.I209I

c.627C>A

1 paper

NM_182919.4

p.L207delFs

c.620_621delCA