Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_182919.4

p.S186L

c.557C>T

Surrounding Variants

1 paper

NM_182919.4

p.S189T

c.566G>C

1 paper

NM_182919.4

p.Q190R

c.569A>G

1 paper

NM_182919.4

p.P181T

c.541C>A

3 papers

NM_182919.4

p.R180C

c.538C>T

1 paper

NM_182919.4

p.S193A

c.577T>G

1 paper

NM_182919.4

p.R195G

c.583C>G

1 paper

NM_182919.4

p.R195Q

c.584G>A

1 paper

NM_182919.4

p.S196A

c.586T>G

1 paper

NM_182919.4

p.R176W

c.526A>T

1 paper

NM_182919.4

p.S199S

c.597C>T

1 paper

NM_182919.4

p.P200H

c.599C>A

1 paper

NM_182919.4

p.S169S

c.507G>A