Varaico: Literature-Extracted Genetic Variants

TICAM1

238 papers

RefSeq Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the T...

Pfam Domains

TRIF-NTDaa 1–148UCSCTRIF N-terminal domain

RHIMaa 676–697UCSCRIP homotypic interaction motif

Gene Aliases

HGNC Name

TIR domain containing adaptor molecule 1

HGNC Alias Symbols

TRIF; TICAM-1; MGC35334; PRVTIRB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_182919.4

p.R141*

c.421C>T

Surrounding Variants

1 paper

NM_182919.4

p.E139D

c.417G>T

1 paper

NM_182919.4

p.R143Q

c.428G>A

2 papers

NM_182919.4

p.T157M

c.470C>T

1 paper

NM_182919.4

p.R123H

c.368G>A

1 paper

NM_182919.4

p.R123delFs

c.367delG

1 paper

NM_182919.4

p.V122I

c.364G>A

8 papers

NM_182919.4

p.S160F

c.479C>T

1 paper

NM_182919.4

p.Q119L

c.356A>T

1 paper

NM_182919.4

p.L165P

c.494T>C

1 paper

NM_182919.4

p.L113M

c.337C>A

1 paper

NM_182919.4

p.S169S

c.507G>A

1 paper

NM_182919.4

p.A111T

c.331G>A