Varaico: Literature-Extracted Genetic Variants

TIMELESS

389 papers

RefSeq Summary

The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelia...

Pfam Domains

TIMELESSaa 24–284UCSCTimeless protein

PF3D7_5thaa 701–802UCSCPF3D7_0210200 fifth domain

HTH_TIMELESSaa 819–873UCSCTIMELESS, tri-helical helix-turn-helix domain

HTH_TIMELESSaa 886–937UCSCTIMELESS, tri-helical helix-turn-helix domain

TIMELESS_Caa 1004–1101UCSCTimeless-like, PAB domain

Gene Aliases

HGNC Name

timeless circadian regulator

HGNC Alias Symbols

hTIM; TIM; TIM1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003920.5

p.L1171P

c.3512T>C

Surrounding Variants

1 paper

NM_003920.5

p.D1174N

c.3520G>A

4 papers

NM_003920.5

p.D1154N

c.3460G>A

2 papers

NM_003920.5

p.G1193E

c.3578G>A

1 paper

NM_003920.5

p.E1123*

c.3367G>T

1 paper

NM_003920.5

p.D1122N

c.3364G>A

1 paper

NM_003920.5

p.A1094fs

c.3280_3281fs

1 paper

NM_003920.5

p.A1094delFs

c.3280delC

6 papers

NM_003920.5

p.R1081R

c.3243A>G

4 papers

NM_003920.5

p.R1081*

c.3241C>T

2 papers

NM_003920.5

p.R1081G

c.3241C>G

1 paper

NM_003920.5

p.F1079L

c.3237C>G

1 paper

NM_003920.5

p.F1079L

c.3237C>A