Varaico: Literature-Extracted Genetic Variants

Gene:TLE2
Variant:p.E671K

TLE2

50 papers

Pfam Domains

TLE_Naa 17–132UCSCGroucho/TLE N-terminal Q-rich domain
TLE_Naa 17–132UCSCGroucho/TLE N-terminal Q-rich domain
WD40aa 448–484UCSCWD domain, G-beta repeat
WD40aa 493–531UCSCWD domain, G-beta repeat
WD40aa 493–531UCSCWD domain, G-beta repeat
WD40aa 539–575UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TLE family member 2, transcriptional corepressor

HGNC Alias Symbols

ESG2; GRG2; ESG; FLJ41188

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003260.5
p.E671K
c.2011G>A
Surrounding Variants
1 paper
NM_003260.5
p.E671A
c.2012A>C
1 paper
NM_003260.5
p.V674M
c.2020G>A
1 paper
NM_001144761.2
p.R674C
c.2020C>T
1 paper
NM_003260.5
p.G683*
c.2047G>T
1 paper
NM_003260.5
p.V654M
c.1960G>A
1 paper
NM_003260.5
p.E650D
c.1950G>T
1 paper
NM_003260.5
p.E650D
c.1950G>C
1 paper
NM_003260.5
p.E650V
c.1949A>T
1 paper
NM_003260.5
p.D643E
c.1929C>G
1 paper
NM_003260.5
p.G683*
c.2047G>T
5 papers
NM_003260.5
p.S705N
c.2114G>A
1 paper
NM_003260.5
p.F629L
c.1887C>G
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