Varaico: Literature-Extracted Genetic Variants

Gene:TLR2
Variant:p.V224V

TLR2

1,316 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–135UCSCLeucine rich repeat
LRRCTaa 561–586UCSCLeucine rich repeat C-terminal domain
TIRaa 640–783UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 2

HGNC Alias Symbols

TIL4; CD282

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001318789.2
p.V224V
c.672G>A
Surrounding Variants
1 paper
NM_001318789.2
p.S222C
c.664A>T
1 paper
NM_001318789.2
p.L227F
c.681G>C
1 paper
NM_001318789.2
p.L227F
c.681G>T
1 paper
NM_001318789.2
p.D219G
c.656A>G
1 paper
NM_001318789.2
p.D231G
c.692A>G
1 paper
NM_001318789.2
p.D231E
c.693T>A
1 paper
NM_001318789.2
p.T232A
c.694A>G
9 papers
NM_001318789.2
p.F217S
c.650T>C
1 paper
NM_001318789.2
p.I216V
c.646A>G
1 paper
NM_001318789.2
p.D233G
c.698A>G
1 paper
NM_001318789.2
p.D235A
c.704A>C
1 paper
NM_001318789.2
p.L214M
c.640C>A
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