Varaico: Literature-Extracted Genetic Variants

TLR3

639 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 51–111UCSCLeucine rich repeat

LRR_8aa 274–332UCSCLeucine rich repeat

LRR_8aa 562–622UCSCLeucine rich repeat

Tlr3_TMDaa 698–730UCSCToll-like receptor 3 trans-membrane domain

TIRaa 755–895UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 3

HGNC Alias Symbol

CD283

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_003265.3

p.Q3K

c.7C>A

Surrounding Variants

2 papers

NM_003265.3

p.Q3L

c.8A>T

1 paper

NM_003265.3

p.T4insFs

c.11dupC

1 paper

NM_003265.3

p.R2G

c.4A>G

1 paper

NM_003265.3

p.T4N

c.11C>A

1 paper

NM_003265.3

p.R2ins0

c.4_6dupAGA

1 paper

NM_003265.3

p.M1T

c.2T>C

4 papers

NM_003265.3

p.M1V

c.1A>G

1 paper

NM_003265.3

p.M1delFs

c.2delT

1 paper

NM_003265.3

p.M1insFs

c.1_2insA

1 paper

NM_003265.3

p.W11insFs

c.32dupG

1 paper

NM_003265.3

p.W11insFs

c.31_32insGG

2 papers

NM_003265.3

p.W11fs

c.31_32fs