Varaico: Literature-Extracted Genetic Variants

TLR3

639 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 51–111UCSCLeucine rich repeat

LRR_8aa 274–332UCSCLeucine rich repeat

LRR_8aa 562–622UCSCLeucine rich repeat

Tlr3_TMDaa 698–730UCSCToll-like receptor 3 trans-membrane domain

TIRaa 755–895UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 3

HGNC Alias Symbol

CD283

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003265.3

p.F17S

c.50T>C

Surrounding Variants

1 paper

NM_003265.3

p.F17L

c.51T>A

2 papers

NM_003265.3

p.F17L

c.49T>C

1 paper

NM_003265.3

p.F17L

c.51T>G

1 paper

NM_003265.3

p.P16P

c.48C>T

1 paper

NM_003265.3

p.P16L

c.47C>T

1 paper

NM_003265.3

p.P16S

c.46C>T

1 paper

NM_003265.3

p.M19delFs

c.55delA

2 papers

NM_003265.3

p.L15W

c.44T>G

1 paper

NM_003265.3

p.L15M

c.43T>A

1 paper

NM_003265.3

p.L20V

c.58C>G

1 paper

NM_003265.3

p.L14P

c.41T>C

1 paper

NM_003265.3

p.L14F

c.40C>T