Varaico: Literature-Extracted Genetic Variants

TLR3

639 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 51–111UCSCLeucine rich repeat

LRR_8aa 274–332UCSCLeucine rich repeat

LRR_8aa 562–622UCSCLeucine rich repeat

Tlr3_TMDaa 698–730UCSCToll-like receptor 3 trans-membrane domain

TIRaa 755–895UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 3

HGNC Alias Symbol

CD283

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003265.3

p.D36Y

c.106G>T

Surrounding Variants

1 paper

NM_003265.3

p.C37S

c.109T>A

2 papers

NM_003265.3

p.C37R

c.109T>C

1 paper

NM_003265.3

p.C37S

c.110G>C

1 paper

NM_003265.3

p.C37insFs

c.110_111insC

1 paper

NM_003265.3

p.C37*

c.111C>A

1 paper

NM_003265.3

p.H39R

c.116A>G

1 paper

NM_003265.3

p.H32Q

c.96T>G

1 paper

NM_003265.3

p.H32R

c.95A>G

1 paper

NM_003265.3

p.L40L

c.120G>A

1 paper

NM_003265.3

p.S31_H32insGG

c.91_95ins6

1 paper

NM_003265.3

p.L42*

c.125T>A

1 paper

NM_003265.3

p.C28G

c.82T>G