Varaico: Literature-Extracted Genetic Variants

TLR3

639 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 51–111UCSCLeucine rich repeat

LRR_8aa 274–332UCSCLeucine rich repeat

LRR_8aa 562–622UCSCLeucine rich repeat

Tlr3_TMDaa 698–730UCSCToll-like receptor 3 trans-membrane domain

TIRaa 755–895UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 3

HGNC Alias Symbol

CD283

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003265.3

p.Q96Q

c.288G>A

Surrounding Variants

1 paper

NM_003265.3

p.C95S

c.284G>C

1 paper

NM_003265.3

p.C95S

c.283T>A

1 paper

NM_003265.3

p.L101S

c.302T>C

1 paper

NM_003265.3

p.K102E

c.304A>G

2 papers

NM_003265.3

p.S88*

c.263C>A

3 papers

NM_003265.3

p.S88*

c.263C>G

1 paper

NM_003265.3

p.S88T

c.262T>A

1 paper

NM_003265.3

p.N109S

c.326A>G

2 papers

NM_003265.3

p.E110K

c.328G>A

1 paper

NM_003265.3

p.V82E

c.245T>A

1 paper

NM_003265.3

p.D81G

c.242A>G

1 paper

NM_003265.3

p.T78S

c.233C>G