Varaico: Literature-Extracted Genetic Variants

TLR3

639 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 51–111UCSCLeucine rich repeat

LRR_8aa 274–332UCSCLeucine rich repeat

LRR_8aa 562–622UCSCLeucine rich repeat

Tlr3_TMDaa 698–730UCSCToll-like receptor 3 trans-membrane domain

TIRaa 755–895UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 3

HGNC Alias Symbol

CD283

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003265.3

p.P880Q

c.2639C>A

Surrounding Variants

1 paper

NM_003265.3

p.V881V

c.2643T>C

1 paper

NM_003265.3

p.K883K

c.2649A>G

1 paper

NM_003265.3

p.G887D

c.2660G>A

1 paper

NM_003265.3

p.A888A

c.2664C>T

1 paper

NM_003265.3

p.M870I

c.2610G>A

1 paper

NM_003265.3

p.M870I

c.2610G>C

1 paper

NM_003265.3

p.M870I

c.2610G>T

6 papers

NM_003265.3

p.M870V

c.2608A>G

1 paper

NM_003265.3

p.H891R

c.2672A>G

1 paper

NM_003265.3

p.G869R

c.2605G>A

1 paper

NM_003265.3

p.G869R

c.2605G>C

1 paper

NM_003265.3

p.R868R

c.2604A>G