Varaico: Literature-Extracted Genetic Variants

TLR4

2,554 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 55–114UCSCLeucine rich repeat

LRR_4aa 150–197UCSCLeucine Rich repeats (2 copies)

LRR_8aa 447–508UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 4

HGNC Alias Symbols

hToll; CD284; TLR-4; ARMD10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138554.5

p.Y794*

c.2382C>G

Surrounding Variants

1 paper

NM_138554.5

p.Y794*

c.2382C>A

1 paper

NM_138554.5

p.Y794C

c.2381A>G

1 paper

NM_138554.5

p.Y794F

c.2381A>T

1 paper

NM_138554.5

p.E796A

c.2387A>C

1 paper

NM_138554.5

p.E798K

c.2392G>A

1 paper

NM_138554.5

p.E798A

c.2393A>C

1 paper

NM_138554.5

p.L788I

c.2362C>A

2 papers

NM_138554.5

p.R787H

c.2360G>A

2 papers

NM_138554.5

p.R787C

c.2359C>T

2 papers

NM_138554.5

p.L802Q

c.2405T>A

3 papers

NM_138554.5

p.G803E

c.2408G>A

1 paper

NM_138554.5

p.G803A

c.2408G>C