Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_003268.6

p.K841K

c.2523A>G

Surrounding Variants

1 paper

NM_003268.6

p.K843R

c.2528A>G

1 paper

NM_003268.6

p.K838R

c.2513A>G

1 paper

NM_003268.6

p.K838E

c.2512A>G

8 papers

NM_003268.6

p.D846G

c.2537A>G

1 paper

NM_003268.6

p.I836L

c.2506A>T

1 paper

NM_003268.6

p.N847S

c.2540A>G

1 paper

NM_003268.6

p.I836L

c.2506A>C

1 paper

NM_003268.6

p.P850L

c.2549C>T

1 paper

NM_003268.6

p.L832P

c.2495T>C

3 papers

NM_003268.6

p.K831K

c.2493A>G

1 paper

NM_003268.6

p.K831E

c.2491A>G

1 paper

NM_003268.6

p.L829L

c.2487T>C