Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.R817G

c.2449A>G

Surrounding Variants

1 paper

NM_003268.6

p.D821A

c.2462A>C

1 paper

NM_003268.6

p.K812T

c.2435A>C

3 papers

NM_003268.6

p.L822F

c.2464C>T

1 paper

NM_003268.6

p.S805A

c.2413T>G

1 paper

NM_003268.6

p.L829L

c.2487T>C

1 paper

NM_003268.6

p.K831E

c.2491A>G

3 papers

NM_003268.6

p.K831K

c.2493A>G

1 paper

NM_003268.6

p.L832P

c.2495T>C

1 paper

NM_003268.6

p.M801I

c.2403G>A

1 paper

NM_003268.6

p.I836L

c.2506A>T

1 paper

NM_003268.6

p.I836L

c.2506A>C

1 paper

NM_003268.6

p.K838E

c.2512A>G