Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003268.6

p.S720R

c.2160T>G

Surrounding Variants

3 papers

NM_003268.6

p.S720R

c.2160T>A

3 papers

NM_003268.6

p.S720R

c.2158A>C

1 paper

NM_003268.6

p.N726N

c.2178C>T

1 paper

NM_003268.6

p.F729V

c.2185T>G

1 paper

NM_003268.6

p.Q708H

c.2124G>T

1 paper

NM_003268.6

p.Q708H

c.2124G>C

1 paper

NM_003268.6

p.P736A

c.2206C>G

1 paper

NM_003268.6

p.R740H

c.2219G>A

1 paper

NM_003268.6

p.L697*

c.2090T>A

8 papers

NM_003268.6

p.D694G

c.2081A>G

3 papers

NM_003268.6

p.R752G

c.2254A>G

1 paper

NM_003268.6

p.D681fs

c.2041_2042fs