Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003268.6

p.M655V

c.1963A>G

Surrounding Variants

1 paper

NM_003268.6

p.M655I

c.1965G>T

1 paper

NM_003268.6

p.M655I

c.1965G>C

1 paper

NM_003268.6

p.M655I

c.1965G>A

1 paper

NM_003268.6

p.L654F

c.1960C>T

1 paper

NM_003268.6

p.L658P

c.1973T>C

1 paper

NM_003268.6

p.C646C

c.1938C>T

11 papers

NM_003268.6

p.I644F

c.1930A>T

1 paper

NM_003268.6

p.C670C

c.2010T>C

1 paper

NM_003268.6

p.L677V

c.2029C>G

1 paper

NM_003268.6

p.D681fs

c.2041_2042fs

1 paper

NM_003268.6

p.G628G

c.1884T>C

1 paper

NM_003268.6

p.L624V

c.1870C>G