Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.P518L

c.1553C>T

Surrounding Variants

1 paper

NM_003268.6

p.H511R

c.1532A>G

1 paper

NM_003268.6

p.V506V

c.1518T>G

1 paper

NM_003268.6

p.L501P

c.1502T>C

1 paper

NM_003268.6

p.L501I

c.1501C>A

1 paper

NM_003268.6

p.L538P

c.1613T>C

1 paper

NM_003268.6

p.A548V

c.1643C>T

7 papers

NM_003268.6

p.L487I

c.1459C>A

1 paper

NM_003268.6

p.M484I

c.1452G>T

1 paper

NM_003268.6

p.M484I

c.1452G>C

1 paper

NM_003268.6

p.M484I

c.1452G>A

1 paper

NM_003268.6

p.D554G

c.1661A>G

1 paper

NM_003268.6

p.L478I

c.1432C>A