Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.N413D

c.1237A>G

Surrounding Variants

1 paper

NM_003268.6

p.G412G

c.1236C>T

1 paper

NM_003268.6

p.L410F

c.1230G>T

1 paper

NM_003268.6

p.L410F

c.1230G>C

1 paper

NM_003268.6

p.V416G

c.1247T>G

1 paper

NM_003268.6

p.L423L

c.1269T>G

1 paper

NM_003268.6

p.I402T

c.1205T>C

1 paper

NM_003268.6

p.I399T

c.1196T>C

1 paper

NM_003268.6

p.N426N

c.1278C>T

1 paper

NM_003268.6

p.L427P

c.1280T>C

1 paper

NM_003268.6

p.H429L

c.1286A>T

1 paper

NM_003268.6

p.R392Q

c.1175G>A

105 papers

NM_003268.6

p.R392*

c.1174C>T