Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.I375S

c.1124T>G

Surrounding Variants

1 paper

NM_003268.6

p.D377N

c.1129G>A

1 paper

NM_003268.6

p.A373T

c.1117G>A

1 paper

NM_003268.6

p.K361R

c.1082A>G

1 paper

NM_003268.6

p.L389_D390insFs

c.1167_1168insC

1 paper

NM_003268.6

p.L391P

c.1172T>C

105 papers

NM_003268.6

p.R392*

c.1174C>T

1 paper

NM_003268.6

p.R392Q

c.1175G>A

2 papers

NM_003268.6

p.Y357C

c.1070A>G

1 paper

NM_003268.6

p.Y357S

c.1070A>C

1 paper

NM_003268.6

p.Y357H

c.1069T>C

2 papers

NM_003268.6

p.N355N

c.1065T>C

1 paper

NM_003268.6

p.S354L

c.1061C>T