Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003268.6

p.L303P

c.908T>C

Surrounding Variants

1 paper

NM_003268.6

p.R306*

c.916C>T

1 paper

NM_003268.6

p.R306G

c.916C>G

1 paper

NM_003268.6

p.V307I

c.919G>A

1 paper

NM_003268.6

p.S296L

c.887C>T

1 paper

NM_003268.6

p.D313Y

c.937G>T

1 paper

NM_003268.6

p.D313E

c.939T>G

1 paper

NM_003268.6

p.D313E

c.939T>A

1 paper

NM_003268.6

p.L293L

c.877C>T

1 paper

NM_003268.6

p.K315E

c.943A>G

1 paper

NM_003268.6

p.V290A

c.869T>C

1 paper

NM_003268.6

p.A286V

c.857C>T

1 paper

NM_003268.6

p.K323K

c.969G>A