Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.S247T

c.740G>C

Surrounding Variants

5 papers

NM_003268.6

p.N248S

c.743A>G

1 paper

NM_003268.6

p.I250I

c.750C>A

1 paper

NM_003268.6

p.T243A

c.727A>G

3 papers

NM_003268.6

p.L258*

c.773T>A

1 paper

NM_003268.6

p.L260R

c.779T>G

1 paper

NM_003268.6

p.H263R

c.788A>G

1 paper

NM_003268.6

p.G266C

c.796G>T

3 papers

NM_003268.6

p.G268R

c.802G>C

3 papers

NM_003268.6

p.G268R

c.802G>A

1 paper

NM_003268.6

p.N225D

c.673A>G

2 papers

NM_003268.6

p.I274delFs

c.821delA

1 paper

NM_003268.6

p.F271_D276del0

c.811_828del18