Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003268.6

p.S199S

c.597C>T

Surrounding Variants

1 paper

NM_003268.6

p.F201L

c.601T>C

2 papers

NM_003268.6

p.L198I

c.592C>A

1 paper

NM_003268.6

p.F201L

c.603T>G

1 paper

NM_003268.6

p.F201L

c.603T>A

1 paper

NM_003268.6

p.S202G

c.604A>G

1 paper

NM_003268.6

p.K196E

c.586A>G

1 paper

NM_003268.6

p.L193I

c.577C>A

1 paper

NM_003268.6

p.S207delFs

c.620_621delGC

1 paper

NM_003268.6

p.S210T

c.629G>C

1 paper

NM_003268.6

p.H188R

c.563A>G

1 paper

NM_003268.6

p.R211K

c.632G>A

1 paper

NM_003268.6

p.I182M

c.546A>G