Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003268.6

p.N96K

c.288C>A

Surrounding Variants

2 papers

NM_003268.6

p.N96K

c.288C>G

1 paper

NM_003268.6

p.L97L

c.291T>C

1 paper

NM_003268.6

p.L94V

c.280C>G

1 paper

NM_003268.6

p.R92K

c.275G>A

1 paper

NM_003268.6

p.A90G

c.269C>G

2 papers

NM_003268.6

p.G103E

c.308G>A

1 paper

NM_003268.6

p.S105N

c.314G>A

1 paper

NM_003268.6

p.I86V

c.256A>G

2 papers

NM_003268.6

p.Y108H

c.322T>C

3 papers

NM_003268.6

p.L84*

c.251T>A

10 papers

NM_003268.6

p.T82I

c.245C>T

1 paper

NM_003268.6

p.Y81*

c.243T>A